What is in Differin Epiduo?

Differin Epiduo contains ADAPALENE 1 mg/g, BENZOYL PEROXIDE 25 mg/g.

What form does Differin Epiduo come in?

It is supplied as a gel taken by the topical route.

Is Differin Epiduo available without a prescription?

Differin Epiduo is listed as an over-the-counter medicine in the FDA directory.

Are there alternatives to Differin Epiduo?

The directory lists 8 other product(s) containing Adapalene. They may differ in strength, form or manufacturer, so check with a pharmacist before switching.

Over the counter

Differin Epiduo

Adapalene and Benzoyl Peroxide

Listed by Galderma Laboratories, L.P.

Strength: 1 mg/g, 25 mg/g
Form: Gel
Route: Topical
Class: Retinoid

What it contains

Adapalene 1 mg/g
Benzoyl Peroxide 25 mg/g

This is a combination product. It is not interchangeable with a single-ingredient medicine containing only one of these.

FDA record

Dosage form	Gel
Route	Topical
Drug class	Retinoid
Approval route	NDA — original brand approval
NDC code	`0299-4908`
FDA application	NDA220736
RxNorm concept	829539
Package sizes listed	3
Marketed since	May 2026

Other products containing Adapalene

See all

Same active ingredient, different manufacturer, strength or form. Products matching on both ingredient and strength are usually interchangeable — but confirm before switching, especially with modified-release forms.

Compare