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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

876 medications

Tick up to 4 to compare.

ibuprofen pm

Diphenhydramine Citrate, Ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Rite Aid Corporation

Not stocked by us — reference only

IBUPROFEN PM

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Safeway

Not stocked by us — reference only

ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Kroger Company

Not stocked by us — reference only

ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

H E B

Not stocked by us — reference only

Ibuprofen PM

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Meijer Distribution Inc

Not stocked by us — reference only

ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

HyVee Inc

Not stocked by us — reference only

ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Publix Super Markets Inc

Not stocked by us — reference only

ibuprofen pm

diphenhydramine citrate and ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

CVS Pharmacy

Not stocked by us — reference only

Industrial Itch and Pain Relief

DIPHENHYDRAMINE HYDROCHLORIDE and Zinc Acetate

Strength
20 mg/mL, 1 mg/mL
Form
Liquid
Class
Copper Absorption Inhibitor; Histamine-…
OTC

R & R Lotion, Inc

Not stocked by us — reference only

itch relief

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

H E B

Not stocked by us — reference only

Itch Relief

Diphenhydramine HCl, Zinc Acetate

Strength
20 mg/mL, 1 mg/mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Meijer, Inc.

Not stocked by us — reference only

Itch Relief

Diphenhydramine HCl, Zinc Acetate

Strength
20 mg/mL, 1 mg/mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Old East Main Co.

Not stocked by us — reference only

Itch Relief

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

CVS Pharmacy

Not stocked by us — reference only

Itch Relief

Diphenhydramine HCl and Zinc Acetate

Strength
1.5 g/76g, .076 g/76g
Form
Aerosol, Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

CVS Pharmacy

Not stocked by us — reference only

Itch Relief

Diphenhydramine HCl, Zinc Acetate

Strength
20 mg/mL, 1 mg/mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Cardinal Health, 110 dba Leader

Not stocked by us — reference only

Itch Relief Cream

Zinc Acetate 0.1%, Diphenhydramine hydrochloride 2%

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Pharmacy Value Alliance LLC

Not stocked by us — reference only

Itch stopping Cream

Diphenhydramine hydrochloride 2%, zinc acetate 0.1%

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Trifecta Pharmaceuticals USA, LLC.

Not stocked by us — reference only

ItchZap

Diphenhydramine Hydrochloride and Zinc Acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Rising Pharma Holdings, Inc.

Not stocked by us — reference only

KINKAN COOL

diphenhydramine hydrochloride, menthol

Strength
1 g/50mL, .5 g/50mL
Form
Liniment
Class
Histamine-1 Receptor Antagonist
OTC

KINKANDO CO., LTD .

Not stocked by us — reference only

leader anti itch

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Ibuprofen PM

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Lil Drug Store Tylenol PM Extra Strength

Acetaminophen and Diphenhydramine Hydrochloride

Strength
500 mg/1, 25 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist
OTC

Lil' Drug Store Products, Inc.

Not stocked by us — reference only

Naproxen Sodium and Diphenhydramine HCL

Strength
25 mg/1, 220 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

TARGET CORPORATION

Not stocked by us — reference only

Naproxen Sodium Diphenhydramine HCL

Strength
25 mg/1, 220 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Walmart

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.