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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

876 medications

Tick up to 4 to compare.

Dr. Sheffield Anti Itch Cream

Anti Itch Cream

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Sheffield Pharmaceuticals LLC

Not stocked by us — reference only

Dr. Simi Pain Reliever PM

Acetaminophen, Diphenhydramine HCl

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

Farmacias De Similares TX LLC

Not stocked by us — reference only

equaline ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

United Natural Foods, Inc. dba UNFI

Not stocked by us — reference only

equaline naproxen sodium pm

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

United Natural Foods, Inc. dba UNFI

Not stocked by us — reference only

Equate Anti Itch

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Wal-Mart Stores Inc

Not stocked by us — reference only

equate ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Wal-Mart Stores Inc

Not stocked by us — reference only

Exchange Select Ibuprofen PM

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Army & Air Force Exchange Service

Not stocked by us — reference only

Extra strength Acetaminophen PM

Acetaminophen 500mg/ Diphenhydramine HCl 25mg

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

TIME CAP LABS INC

Not stocked by us — reference only

Extra Strength Itch Relief

Diphenhydramine HCl and Zinc Acetate

Strength
20 mg/g, 1 mg/g
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Meijer Distribution Inc

Not stocked by us — reference only

Extra Strength Itch Relief

Diphenhydramine HCl and Zinc Acetate

Strength
20 mg/g, 1 mg/g
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Chain Drug Marketing Association Inc

Not stocked by us — reference only

Extra Strength Itch Stopping

Itch Stopping Cream

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Universal Distribution Centre LLC

Not stocked by us — reference only

Extra Strength NiteTime Pain Relief

Acetaminophen 500 mg,Diphenhydramine Hydrochloride 25 mg Tablet

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

WALGREENS

Not stocked by us — reference only

EXTRA STRENGTH WAL-DRYL ITCH RELIEF

DIPHENHYDRAMINE, ZINC ACETATE

Strength
20 mg/mL, 1 mg/mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

WALGREEN CO

Not stocked by us — reference only

Family Wellness

DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Zhejiang Jingwei Pharmaceutical Co., Ltd.

Not stocked by us — reference only

Family Wellness

DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

FRONT PHARMACEUTICAL PLC

Not stocked by us — reference only

foster and thrive anti itch cream

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Strategic Sourcing Services LLC

Not stocked by us — reference only

foster and thrive ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Strategic Sourcing Services LLC

Not stocked by us — reference only

good neighbor pharmacy ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Amerisource Bergen

Not stocked by us — reference only

good sense ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

L. Perrigo Company

Not stocked by us — reference only

good sense itch relief

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

L. Perrigo Company

Not stocked by us — reference only

good sense naproxen sodium

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

L. Perrigo Company

Not stocked by us — reference only

GoodSense Anti-Itch

Diphenhydramine HCl, Zinc Acetate

Strength
2 g/100mL, .1 g/100mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Geiss, Destin & Dunn, Inc

Not stocked by us — reference only

Ibuprofen PM

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Walgreen Company

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.