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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

876 medications

Tick up to 4 to compare.

Childrens Benadryl Allergy Plus Congestion

Diphenhydramine hydrochloride and Phenylephrine hydrochloride

Strength
12.5 mg/5mL, 5 mg/5mL
Form
Solution
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Kenvue Brands LLC

Not stocked by us — reference only

Childrens Cold and Cough Nighttime

Diphenhydramine HCl, Phenylephrine HCl

Strength
6.25 mg/5mL, 2.5 mg/5mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Safeway, Inc.

Not stocked by us — reference only

Childrens Nighttime Cold and Cough

Diphenhydramine HCl, Phenylephrine HCl

Strength
6.25 mg/5mL, 2.5 mg/5mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

KinderFarms, LLC

Not stocked by us — reference only

Cold and Congestion Childrens Nighttime

Diphenhydramine HCI, Phenylephrine HCl

Strength
12.5 mg/10mL, 5 mg/10mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Walgreens

Not stocked by us — reference only

CoreTex Anti-Itch Gel

camphor, diphenhydramine, zinc acetate

Strength
.1 g/100mL, 2 g/100mL, 1 g/100mL
Form
Gel
Class
Copper Absorption Inhibitor; Histamine-…
OTC

CoreTex Products Inc

Not stocked by us — reference only

CounterAct PM

Acetaminophen and Diphenhydramine

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

Melaleuca, Inc.

Not stocked by us — reference only

CVS Extra Strength Itch Stopping

Diphenhydramine hydrochloride and Zinc acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

CVS

Not stocked by us — reference only

CVS Regular Strength Itch Stopping

Diphenhydramine hydrochloride, Zinc acetate

Strength
10 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

CVS

Not stocked by us — reference only

dg health Ibuprofen pm

diphenhydramine citrate and ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Dolgencorp Inc

Not stocked by us — reference only

dg health naproxen sodium pm

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Dolgencorp Inc

Not stocked by us — reference only

Dimetapp Nighttime Cold and Congestion

DIPHENHYDRAMINE HYDROCHLORIDE and PHENYLEPHRINE HYDROCHLORIDE

Strength
6.25 mg/5mL, 2.5 mg/5mL
Form
Solution
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Foundation Consumer Brands

Not stocked by us — reference only

Diphenhydramine HCl and Ibuprofen

Strength
25 mg/1, 200 mg/1
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Aurohealth LLC

Not stocked by us — reference only

Diphenhydramine HCl and Ibuprofen

Strength
25 mg/1, 200 mg/1
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Aurohealth LLC

Not stocked by us — reference only

Diphenhydramine HCl and Ibuprofen

Strength
25 mg/1, 200 mg/1
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Aurohealth LLC

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Extra Strength Itch Relief

Strength
1.52 g/76g, .076 g/76g
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Walgreen Company

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Extra Strength Itch Relief Continuous Spray

Strength
1.5 g/76g, .075 g/76g
Form
Aerosol, Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Topco Associates LLC

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Extra Strength Itch Relief

Strength
1.52 g/76g, .076 g/76g
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

HEB

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Extra Strength Itch Relief

Strength
1.52 g/76g, .076 g/76g
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Meijer Distribution Inc

Not stocked by us — reference only

diphenhydramine hcl and zinc acetate

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Padagis Israel Pharmaceuticals Ltd

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Anti-Itch Continuous Spray

Strength
1.5 g/88mL, .075 g/88mL
Form
Aerosol, Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Wal-Mart Stores, Inc.

Not stocked by us — reference only

Diphenhydramine HCl and Zinc Acetate

Extra Strength Itch Relief

Strength
1.52 g/88mL, .076 g/88mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

VALU MERCHANDISERS, CO

Not stocked by us — reference only

Discount Drug Mart Extra Strength Itch Stopping

Diphenhydramine hydrochloride and Zinc acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Discount Drug Mart

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.