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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

876 medications

Tick up to 4 to compare.

Aleve PM

DIPHENHYDRAMINE HYDROCHLORIDE and NAPROXEN SODIUM

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Bayer HealthCare LLC.

Not stocked by us — reference only

ALL NIGHT PAIN RELIEF PM

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Walgreen Company

Not stocked by us — reference only

Allergy Plus Congestion Relief

Diphenhydramine HCl, Phenylephrine HCl

Strength
25 mg/1, 10 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED

Not stocked by us — reference only

Allergy Plus Sinus Relief

Diphenhydramine HCl and Phenylephrine HCl

Strength
25 mg/1, 10 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Rite Aid Corporation

Not stocked by us — reference only

Allergy Relief Plus Congestion

Diphenhydramine HCl, Phenylephrine HCl

Strength
25 mg/1, 10 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Walgreen Company

Not stocked by us — reference only

anti itch

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Kroger Company

Not stocked by us — reference only

Anti Itch

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Meijer Distribution Inc

Not stocked by us — reference only

Anti-itch

diphenhydramine hydrochloride and zinc acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Target Corporation

Not stocked by us — reference only

Anti-Itch

Diphenhydramine hydrochloride and Zinc acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Amerisource Bergen

Not stocked by us — reference only

ANTI-ITCH

ZINC ACETATE , DIPHENHYDRAMINE

Strength
1 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

OL PHARMA TECH, LLC

Not stocked by us — reference only

Anti-Itch Cream

Diphenhydramine hydrochloride 2%, zinc acetate 0.1%

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Trifecta Pharmaceuticals USA, LLC.

Not stocked by us — reference only

Anti-Itch Cream

Diphenhydramine hydrochloride 2%, zinc acetate 0.1%

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Chain Drug Marketing Association Inc.

Not stocked by us — reference only

Banophen

Diphenhydramine Hydrochloride, Zinc Acetate

Strength
2 g/100g, .1 g/100g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Major Pharmaceuticals

Not stocked by us — reference only

basic care ibuprofen pm

diphenhydramine citrate, ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Amazon.com Services LLC

Not stocked by us — reference only

basic care naproxen sodium pm

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

Amazon.com Services LLC

Not stocked by us — reference only

Benadryl Allergy Plus Congestion

Diphenhydramine Hydrochloride and Phenylephrine Hydrochloride

Strength
25 mg/1, 10 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Kenvue Brands LLC

Not stocked by us — reference only

Benadryl Extra Strength Itch Cooling

Diphenhydramine Hydrochloride and Zinc Acetate

Strength
20 mg/mL, 1 mg/mL
Form
Spray
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Kenvue Brands LLC

Not stocked by us — reference only

Benadryl Extra Strength Itch Stopping

Diphenhydramine Hydrochloride and Zinc Acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Kenvue Brands LLC

Not stocked by us — reference only

Benadryl Original Strength Itch Stopping

Diphenhydramine Hydrochloride and Zinc Acetate

Strength
10 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Kenvue Brands LLC

Not stocked by us — reference only

Care One Ibuprofen PM

diphenhydramine citrate and ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

American Sales Company

Not stocked by us — reference only

CAREALL Anti-Itch

diphenhydramine hydrochloride and zinc acetate cream

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

New World Imports, Inc

Not stocked by us — reference only

careone naproxen sodium pm

diphenhydramine hydrochloride, naproxen sodium

Strength
25 mg/1, 220 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC Generic

American Sales Company

Not stocked by us — reference only

Caring Mill Anti-Itch Cream

Diphenhydramine Hydrochloride and Zinc Acetate

Strength
20 mg/g, 1 mg/g
Form
Cream
Class
Copper Absorption Inhibitor; Histamine-…
OTC

Veridian Healthcare

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.