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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

2,765 medications

Tick up to 4 to compare.

NOCOLD-F

ACETAMINOPHENE. CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMI…

Strength
200 mg/30mL, 2.5 mg/30mL, 15 mg/30mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist; Sigma-…
OTC

Lydia Co., Ltd.

Not stocked by us — reference only

Non-Drowsy Sinus Severe, Circle K

Acetaminophen, Guaifenesin, Phenylephrine HCl caplet, film-coated

Strength
325 mg/1, 200 mg/1, 5 mg/1
Form
Tablet, Film Coated
Class
Expectorant; alpha-1 Adrenergic Agonist
OTC

Lil' Drug Store products, Inc.

Not stocked by us — reference only

Norel AD

acetaminophen, chlorpheniramine maleate, and phenylephrine HCl

Strength
325 mg/1, 4 mg/1, 10 mg/1
Form
Tablet, Multilayer
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

U.S. PHARMACEUTICAL CORPORATION

Not stocked by us — reference only

NOTTS - Pain Relief PM

Acetaminophen, Diphenhydramine hydrochloride

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

VIVUNT PHARMA LLC

Not stocked by us — reference only

NOTTS - Tension Headache

Acetaminophen, Caffeine

Strength
500 mg/1, 65 mg/1
Form
Tablet
Class
Central Nervous System Stimulant; Methy…
OTC

VIVUNT PHARMA LLC

Not stocked by us — reference only

Nuvicare DayTime Cold and Flu Softgel

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLO…

Strength
325 mg/1, 10 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

NUVICARE LLC

Not stocked by us — reference only

Nuvicare DayTime Cold and Flu Softgel

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLO…

Strength
325 mg/1, 10 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

NUVICARE LLC

Not stocked by us — reference only

Nuvicare NightTime Cold and Flu Softgel

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, Doxylamine succinate

Strength
325 mg/1, 15 mg/1, 6.25 mg/1
Form
Capsule, Liquid Filled
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

NUVICARE LLC

Not stocked by us — reference only

Nuvicare NightTime Cold and Flu Softgel

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, Doxylamine succinate

Strength
325 mg/1, 15 mg/1, 6.25 mg/1
Form
Capsule, Liquid Filled
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

NUVICARE LLC

Not stocked by us — reference only

NyQuil Severe Plus VapoCOOL Cold and Flu

Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and…

Strength
325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1
Form
Tablet, Coated
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Lil' Drug Store Products, Inc.

Not stocked by us — reference only

NyQuil Severe Plus VapoCOOL Cold and Flu, CVP HEALTH

Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and…

Strength
325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1
Form
Tablet, Coated
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Lil' Drug Store Products, Inc.

Not stocked by us — reference only

NyQuil Severe Plus VapoCOOL Cold and Flu, TRAVEL BASIX

Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and…

Strength
325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1
Form
Tablet, Coated
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Lil' Drug Store Products, Inc.

Not stocked by us — reference only

Original Night-Time MULTI-SYMPTOM COLD/FLU RELIEF

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE

Strength
650 mg/30mL, 30 mg/30mL, 12.5 mg/30mL
Form
Liquid
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Discount Drug Mart

Not stocked by us — reference only

Otis Clapp Mygrex

ACETAMINOPHEN, PHENYLEPHRINE HYDROCHLORIDE

Strength
500 mg/1, 5 mg/1
Form
Tablet
Class
alpha-1 Adrenergic Agonist
OTC

Unifirst First Aid Corporation

Not stocked by us — reference only

Otis Clapp Valihist

ACETAMINOPHEN,CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HYDROCHLORIDE

Strength
325 mg/1, 2 mg/1, 5 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist; alpha-…
OTC

Unifirst First Aid Corporation

Not stocked by us — reference only

Overnight Cold and Flu

Acetaminophen, Dextromethorphan HBr, Triprolidine HCl

Strength
650 mg/20mL, 20 mg/20mL, 2.5 mg/20mL
Form
Solution
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

WALGREENS CO

Not stocked by us — reference only

Overnight Cold and Flu

Acetaminophen, Dextromethorphan HBr, Triprolidine HCl

Strength
650 mg/20mL, 20 mg/20mL, 2.5 mg/20mL
Form
Solution
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

RARITAN PHARMACEUTICALS

Not stocked by us — reference only

Oxycodone and Acetaminophen

Strength
325 mg/1, 10 mg/1
Form
Tablet
Class
Opioid Agonist
Rx only Schedule II Generic

AvPAK

Not stocked by us — reference only

Oxycodone and Acetaminophen

Strength
325 mg/1, 2.5 mg/1
Form
Tablet
Class
Opioid Agonist
Rx only Schedule II Generic

Granules Pharmaceuticals Inc.

Not stocked by us — reference only

OXYCODONE AND ACETAMINOPHEN

Strength
325 mg/1, 7.5 mg/1
Form
Tablet
Class
Opioid Agonist
Rx only Schedule II Generic

DIRECT RX

Not stocked by us — reference only

Pain and Sinus

Acetaminophen and Phenylephrine

Strength
500 mg/1, 5 mg/1
Form
Tablet
Class
alpha-1 Adrenergic Agonist
OTC

JHK Inc dba American Safety & First Aid

Not stocked by us — reference only

Pain and Sinus Reliever

Acetaminophen and Phenylephrine

Strength
500 mg/1, 5 mg/1
Form
Tablet
Class
alpha-1 Adrenergic Agonist
OTC

JHK DBA American Safety & First Aid

Not stocked by us — reference only

Pain Relief Acetaminophen PM

Acetaminophen and Diphenhydramine HCl

Strength
500 mg/1, 25 mg/1
Form
Tablet, Coated
Class
Histamine-1 Receptor Antagonist
OTC

Rite Aid Corporation

Not stocked by us — reference only

Pain Relief Acetaminophen PM Extra Strength

Acetaminophen and Diphenhydramine HCl

Strength
500 mg/1, 25 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist
OTC

Rite Aid Corporation

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.