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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

2,765 medications

Tick up to 4 to compare.

Leader Daytime Severe Cold and Flu Relief

acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephr…

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Tablet, Film Coated
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Dual Action Pain Reliever

Acetaminophen, Ibuprofen

Strength
250 mg/1, 125 mg/1
Form
Tablet, Film Coated
Class
Nonsteroidal Anti-inflammatory Drug
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Migraine Relief

Acetaminophen, Aspirin, Caffeine

Strength
250 mg/1, 250 mg/1, 65 mg/1
Form
Tablet, Film Coated
Class
Central Nervous System Stimulant; Methy…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

leader migraine relief

acetaminophen, aspirin, caffeine

Strength
250 mg/1, 250 mg/1, 65 mg/1
Form
Tablet, Film Coated
Class
Central Nervous System Stimulant; Methy…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

LEADER MS Flu Relief Nighttime

Acetaminophen, Chlorpheniramine Maleate and Dextromethophan HBr

Strength
1000 mg/1, 4 mg/1, 30 mg/1
Form
Powder, For Solution
Class
Histamine-1 Receptor Antagonist; Sigma-…
OTC

CARDINAL HEALTH 110, LLC. DBA LEADER

Not stocked by us — reference only

LEADER Multi Symptom Flu Relief Daytime Max Strength

Acetaminophen, Dextromethorphan HBr

Strength
1000 mg/1, 30 mg/1
Form
Powder, For Solution
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

CARDINAL HEALTH 110, LLC. DBA LEADER

Not stocked by us — reference only

Leader Nighttime Cold and Flu

Acetaminophen, Dextromethorphan HBr, Doxylamine succinate

Strength
650 mg/30mL, 30 mg/30mL, 12.5 mg/30mL
Form
Solution
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Nighttime Cold and Flu

Acetaminophen, Dextromethorphan HBr, Doxylamine succinate

Strength
650 mg/30mL, 30 mg/30mL, 12.5 mg/30mL
Form
Solution
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

leader tussin cf

Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephr…

Strength
650 mg/20mL, 20 mg/20mL, 400 mg/20mL, 1…
Form
Solution
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

LEADER TUSSIN CF

acetaminophen, dextromethorphan hydrobromide, guaifenesin

Strength
650 mg/20mL, 20 mg/20mL, 400 mg/20mL
Form
Solution
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Vapor Ice Cold and Flu

acetaminophen, dextromethorphan hydrobromide

Strength
325 mg/1, 10 mg/1
Form
Tablet, Film Coated
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Lil Drug Store Tylenol Cold plus Flu Severe

Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenyl…

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Tablet, Film Coated
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Lil Drug Store Products, Inc

Not stocked by us — reference only

Lil Drug Store Tylenol Sinus Severe

Acetaminophen, Guaifenesin, and Phenylephrine Hydrochloride

Strength
325 mg/1, 200 mg/1, 5 mg/1
Form
Tablet, Coated
Class
Expectorant; alpha-1 Adrenergic Agonist
OTC

Lil Drug Store Products, Inc

Not stocked by us — reference only

MAX Cold, Flu, and Sore Throat

ACETAMINOPHEN,DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN , PHENYLEPHR…

Strength
650 mg/20mL, 20 mg/20mL, 400 mg/20mL, 1…
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

H E B

Not stocked by us — reference only

MAXIMUM STRENGHT DAY COLD AND FLU FORMULA

ACETAMINOPHEN, DEXTROMETHORPHAN, PHENYLEPHRINE HCL

Strength
325 mg/1, 10 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

FAMILY DOLLAR

Not stocked by us — reference only

Maximum Strength Cold and Flu

ACETAMINOPHEN, GUAIFENESIN, DEXTROMETHORPHAN HYDROBROMIDE, and PHENYL…

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Walgreens

Not stocked by us — reference only

MAXIMUM STRENGTH COLD AND FLU

Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

TARGET CORP

Not stocked by us — reference only

MAXIMUM STRENGTH COLD AND FLU

ACETAMINOPHEN,DEXTROMETHORPHAN HYDROBROMIDE,GUAIFENESIN,PHENYLEPHRINE…

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

CVS Pharmacy, Inc

Not stocked by us — reference only

Maximum Strength Cold Flu and Sore Throat

Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl

Strength
650 mg/20mL, 20 mg/20mL, 400 mg/20mL, 1…
Form
Solution
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

KROGER COMPANY

Not stocked by us — reference only

Maximum Strength Cold Tabs

acetaminophen, dextromethorphan hydrobromide, guaifenesin, and phenyl…

Strength
325 mg/1, 10 mg/1, 100 mg/1, 5 mg/1
Form
Capsule, Coated
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

JHK DBA American Safety & First Aid

Not stocked by us — reference only

Maximum Strength Congestion and Headache

Acetaminophen, Dextromethorphan hydrobromide, and Phenylephrine hydro…

Strength
325 mg/1, 10 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Walgreens

Not stocked by us — reference only

Maximum strength Max Cold and Sinus

ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HCl

Strength
650 mg/20mL, 400 mg/20mL, 10 mg/20mL
Form
Liquid
Class
Expectorant; alpha-1 Adrenergic Agonist
OTC

AptaPharma Inc.

Not stocked by us — reference only

Maximum Strength Mucinex Fast-Max Cold and Flu

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYL…

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Capsule, Liquid Filled
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Reckitt Benckiser LLC

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.